Viability Assay:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Flow Cytometry:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Clonogenic Assay:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Control:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Western Blot:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Transfection:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
MANN-WHITNEY:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Inhibition:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Mutagenesis:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Quantitative RT-PCR:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Expressing:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Reverse Transcription Polymerase Chain Reaction:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Amplification:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Immunohistochemical staining:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Knockdown:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
shRNA:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Plasmid Preparation:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Infection:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Sequencing:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Derivative Assay:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Virus:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Cell Culture:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
Concentration Assay:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
MTT Assay:Article Title: The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer
Article Snippet: Human Non-Small Cell Lung Carcinoma (NSCLC) cell lines (H460, A549, H1299, H2170, H3255, H460, PC9, CALU-1, H1975, H226, H358, HCC827) were authenticated by DNA STR profiling (ATCC cell line Authentification Service, LGC standards, Molsheim, France) and routinely tested for mycoplasma contamination.. Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).Parental and cisplatin-resistant cells derived from H460 and A549 NSCLC cells were obtained by continuous exposure to cisplatin according to ( ).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Article Snippet: Human colorectal cancer (CRC) cell lines (HCT116, HT-29, SW480, LoVo, and DLD-1), a normal colon fibroblast cell line (CCD-18Co), and human non-small cell lung carcinoma (NSCLC) cell lines (HCC827, H820, H1975, H460, and A549) were obtained from the American Type Culture Collection (Manassas, VA, USA).. The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).The CRC cell lines SNU-70 and SNU-796 were purchased from the Korea Cell Line Bank (Seoul, South Korea).
Article Title: Hyaluronic Acid Decorated Naringenin Nanoparticles: Appraisal of Chemopreventive and Curative Potential for Lung Cancer
Article Snippet: Human non-small-cell lung carcinoma (NSCLC) cell lines (A549) were obtained from American Type Culture Collection (ATCC, Rockville, MD, USA).. Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.Cells were maintained in appropriate culture medium in Dulbecco’s Modified Eagle’s Medium DMEM supplemented with 10% fetal bovine serum and 1% antibiotic (penicillin) solution.
Article Title: Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells
Article Snippet: Human non-small cell lung carcinoma (NSCLC) cell lines (A549, H460, H1299, H1355, H1703 and SKLU-1) were purchased from ATCC (Manassas, VA, USA).. The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).The cells were cultured in Dulbecco’s modified Eagle’s medium (Gibco-BR, Grand Island, NY, USA), with 10% fetal bovine serum purchased from Atlanta Biologicals (Lawrenceville, GA, USA), 100 U/ml penicillin, and 100 mg/ml streptomycin purchased from Biosource International (Camarillo, CA, USA).
Article Title: Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Article Snippet: Cells and Primary Tumor.Cells and Primary Tumor.. Human non-small-cell lung carcinoma (NSCLC) cell lines were obtained from the American Type Culture Collection (Manassas, VA) or the National Cancer Institute: NCI-A549, NCI-H1975, NCI-H299, NCI-H1993, and NCI-H1373 (adenocarcinoma), NCI-H647 and NCI-H1703 (squamous cell carcinoma of the lung [SCC]).. Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.Human primary small-cell lung carcinoma (SCLC) cells, transduced with thymidine kinase/green fluorescent protein/luciferase triple-fusion gene and named AC3-TGL, were previously described ( 14 ) and obtained from J. Massagué.
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